LOVD GRN homepage

General information
Gene name Granulin
Gene symbol GRN
Chromosome Location 17q21.32
Database location grenada.lumc.nl
Curator LOVD-team, but with Curator vacancy and Sara Mole
PubMed references View all (unique) PubMed references in the GRN database
Date of creation April 29, 2010
Last update January 05, 2013
Version GRN130105
Add sequence variant Submit a sequence variant
First time submitters Register here
Reference sequence file coding DNA reference sequence for describing sequence variants
Genomic refseq ID NG_007886.1
Transcript refseq ID NM_002087.2
Exon/intron information Exon/intron information table
Total number of unique DNA variants reported 0
Total number of individuals with variant(s) 0
Total number of variants reported 0
Subscribe to updates of this gene
See also the NCL mutation and patient database - CLN11/GRN
The establishment of this gene variant database (LSDB) was supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement nÂș 200754 - the GEN2PHEN project.

Graphical displays and utilities
Summary tables Summary of all sequence variants in the GRN database, sorted by type of variant (with graphical displays and statistics)
Reading-frame checker The Reading-frame checker generates a prediction of the effect of whole-exon changes
UCSC Genome Browser Show variants in the UCSC Genome Browser (compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
Homepage http://www.LOVD.nl/GRN
HGNC 4601
Entrez Gene 2896
OMIM - Gene 138945
OMIM - Disease #1 aphasia, primary progressive (PPA)
OMIM - Disease #2 frontotemporal lobar degeneration with ubiquitin-positive inclusions
OMIM - Disease #3 ceroid lipofuscinosis, neuronal, type 11 (CLN-11)
UniProtKB (SwissProt/TrEMBL) Q9UCH0
GeneCards GRN
GeneTests GRN
External link #1 NCL mutation and patient database - CLN11/GRN
External link #2 Orphanet

Copyright & disclaimer
The contents of this LOVD database are the intellectual property of the respective curator(s). Any unauthorised use, copying, storage or distribution of this material without written permission from the curator(s) will lead to copyright infringement with possible ensuing litigation. Copyright © 2016. All Rights Reserved. For further details, refer to Directive 96/9/EC of the European Parliament and the Council of March 11 (1996) on the legal protection of databases.

We have used all reasonable efforts to ensure that the information displayed on these pages and contained in the databases is of high quality. We make no warranty, express or implied, as to its accuracy or that the information is fit for a particular purpose, and will not be held responsible for any consequences arising out of any inaccuracies or omissions. Individuals, organisations and companies which use this database do so on the understanding that no liability whatsoever either direct or indirect shall rest upon the curator(s) or any of their employees or agents for the effects of any product, process or method that may be produced or adopted by any part, notwithstanding that the formulation of such product, process or method may be based upon information here provided.