LOVD LRRK2 homepage

General information
Gene name LEUCINE-RICH REPEAT KINASE 2
Gene symbol LRRK2
Chromosome Location 12q12
Database location The Parkinson's Institute
Curator The Parkinson's Institute
PubMed references View all (unique) PubMed references in the LRRK2 database
Date of creation May 27, 2008
Last update June 04, 2012
Version LRRK2 120604
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GenBank reference NM_198578
Transcript refseq ID NM_198578.3
Total number of unique DNA variants reported 26
Total number of individuals with variant(s) 159
Total number of variants reported 159
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Graphical displays and utilities
Summary tables Summary of all sequence variants in the LRRK2 database, sorted by type of variant (with graphical displays and statistics)
UCSC Genome Browser Show variants in the UCSC Genome Browser (compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Sequence variant tables
Unique sequence variants Listing of all unique sequence variants in the LRRK2 database, without patient data
Complete sequence variant listing Listing of all sequence variants in the LRRK2 database
Variants with no known pathogenicity Listing of all LRRK2 variants reported to have no noticeable phenotypic effect (note: excluding variants of unknown effect)

Search the database
By type of variant View all sequence variants of a certain type
Simple search Query the database by selecting the most important variables (exon number, type of variant, disease phenotype)
Advanced search Query the database by selecting a combination of variables
Based on patient origin View all variants based on your patient origin search terms

Links to other resources
HGNC 18618
OMIM - Gene 609007
OMIM - Disease PARK8
HGMD LRRK2
GeneTests LRRK2
External link Orphanet